Hydroxytyrosol is the major component of the phenolic fraction of olives, which is known for its antioxidant properties. Hydroxytyrosol is a water and lipid-soluble molecule that is an efficient scavenger of peroxyl radicals.8 Experiments demonstrate that hydroxytyrosol effectively counteracts the cytotoxic effects of reactive oxygen species (ROS) in various human cellular systems. In studies using hydroxytyrosol pre-incubated cells, it was found that damage due to oxidative stress, such as lipid peroxidation and alterations of cell permeability, could be prevented and that hydroxytyrosol exerted a protective effect against H2O2 induced oxidative hemolysis.9
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