Cholesterol

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The scientific evidence presented here suggests that the use of various nutrients have the ability to reduce the risks of certain forms of cancer, cardiovascular disease, diabetes, dementia and memory loss, lung disease, joint pain, arthritis, liver disease, obesity, and metabolic function. However, the FDA has not yet determined that this scientific evidence is conclusive. Consult your physician for additional information.

Visioli F, Bellomo G, Montedoro G, Galli C (1995) Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. Atherosclerosis 117:25-32.
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Wiseman SA, Mathot JNNJ, de Fouw NJ, Tijburg LBM (1996) Dietary non-tocopherol antioxidants present in extra virgin olive oil increase the resistance of low density lipoproteins to oxidation in rabbits. Atherosclerosis 120:15-23.
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González-Santiago M, Martin-Bautista E, Carrero JJ, Fonollá J, Baró L, Bartolomé MV, Gil-Loyzaga P, and López-Huertas E (2006) One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis 188:35–42.
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Ramirez-Tortosa MC, Urbano G, López-Jurado M, Nestares T, Gomez MC, Mir A, Ros E, Mataix J, and Gil A (1999) Extra-Virgin Olive Oil Increases the Resistance of LDL to Oxidation More than Refined Olive Oil in Free-Living Men with Peripheral Vascular Disease. J. Nutr. 129: 2177–2183.
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Togna GI, Togna AR, Franconi M, Marra C, and Guiso M (2003) Olive Oil Isochromans Inhibit Human Platelet Reactivity. J. Nutr. 133:2532–2536.
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Manna C, D'Angelo S, Migliardi V, Loffredi E, Mazzoni O, Morrica P, Galletti P, AND Zappia V (2002) Protective Effect of the Phenolic Fraction from Virgin Olive Oils against Oxidative Stress in Human Cells. J. Agric. Food Chem. 50:6521−6526.
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Wahle K, Caruso D, Ochoa JJ, and Quiles JL (2004) Olive Oil and Modulation of Cell Signaling in Disease Prevention. Lipids 39:1223-1231.
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Maria González-Santiago, Juristo Fonollá, Eduardo Lopez-Huertas (2010) Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins. Pharmacological Research 61 (2010) 364–370
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Heather I. Katcher, PhD, RD, Alison M. Hill, PhD, Julie L.G. Lanford, MPH, RD, Janey S.Yoo, MS, RD, PennyM. Kris-Etherton, PhD, RD (2009) Lifestyle Approaches and Dietary Strategies to Lower LDL-Cholesterol and Triglycerides and Raise HDL-Cholesterol. Endocrinol Metab Clin N Am 38 (2009) 45–78
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